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>Synthetic Blood For Soldiers On Battlefield? Infection-Free Transfusions Soon Likely

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British scientists to create ‘synthetic’ blood

Human embryos will be used to make an unlimited supply for infection-free transfusions
By Steve Connor, Science Editor
Monday, 23 March 2009

Scientists in Britain plan to become the first in the world to produce unlimited amounts of synthetic human blood from embryonic stem cells for emergency infection-free transfusions.
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A major research project is to be announced this week that will culminate in three years with the first transfusions into human volunteers of “synthetic” blood made from the stem cells of spare IVF embryos. It could help to save the lives of anyone from victims of traffic accidents to soldiers on a battlefield by revolutionising the vital blood transfusion services, which have to rely on a network of human donors to provide a constant supply of fresh blood.
The multimillion-pound deal involving NHS Blood and Transplant, the Scottish National Blood Transfusion Service and the Wellcome Trust, the world’s biggest medical research charity, means Britain will take centre stage in the global race to develop blood made from embryonic stem cells. The researchers will test human embryos left over from IVF treatment to find those that are genetically programmed to develop into the “O-negative” blood group, which is the universal donor group whose blood can be transfused into anyone without fear of tissue rejection.
This blood group is relatively rare, applicable to about 7 per cent of the population, but it could be produced in unlimited quantities from embryonic stem cells because of their ability to multiply indefinitely in the laboratory.

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